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  4. Wen-Chin Yang Assistant Professor

Wen-Chin Yang Assistant Professor

Wen-Chin Yang Assistant Professor
Education: Ph.D., Université de la Méditerranée, France
Field of Specialization: Drug discovery, Immunology, and Biotechnology
Lab: Academia Sinica
TEL: 886-2-27872076
E-mail: wcyang@sinica.edu.tw
Website: http://abrc.sinica.edu.tw/pi/?id=wcy&lang=En  

Refereed Papers

  1. Chang C.L.T., Chung C.Y., Kuo C.H., Kuo T.F., Yang C.W.*, Yang W.C.*. (2016) Beneficial Effect of Bidens pilosa on Body Weight Gain, Food Conversion Ratio, Gut Bacteria and Coccidiosis in Chickens. PLoS One, 11(1):e0146141 (RF= 11/63; IF=3.057).
  2. Chung, C.Y. +, Yang, W.C.+ ,  Liang, C.L., Liu,H.Y., Lai, S.K., Chang C.L.T. (2016) Cytopiloyne,apolyacetylenicglucosidefrom Bidens pilosa, actsasa novel anticandidal agent via regulationof macrophages, Journal of Ethnopharmacology, 184 :72-80 (co-first author) (RF= 2/24; IF=3.055).
  3. Chang C.L.T., Yang C.Y., Muthamilselvan, T.*, Yang W.C.*. (2016) Field trial of medicinal plant, Bidens pilosa, against eimeriosis in broilers, Scientific Reports, 6 :24692 (RF= 7/63; IF=5.228).
  4. Liang, Y.C., Yang, M.T., Lin, C.J., Chang, C.L.T.*, Yang W.C.*. (2016) Bidens pilosa and its active compound inhibit adipogenesis and lipid accumulation via down-modulation of the C/EBP and PPARγ pathways, Scientific Reports, 6:24285 (RF= 7/63; IF=5.228).
  5. Muthamilselvan, T., Kuo, T.F., Wu, Y.C., Yang W.C.*. (2016) Herbal remedies for coccidiosis control: A review of plants, compounds and anticoccidial actions. Evidence-Based Complementary and Alternative Medicine, 2657981 (R/C=10/26; IF=1.740)
  6. Wei, W.C., Lin, S.Y., Lan, C.W., Huang, Y.C., Lin, C.Y., Hsiao, P.W., Chen, Y.R., Yang, W.C. and Yang*, N.S. (2016) Inhibiting MDSC differentiation from bone marrow with phytochemical polyacetylenes drastically impairs tumor metastasis. Scientific Reports, 6:27917 (RF= 7/63; IF=5.228).
  7. Chung,C.Y.+, Yang, W. C.+, Liang, C.L., Liu, H.Y., Lai, S.K., Chang, C.L.T. * (2016) Data on the effect of Cytopiloyne against Listeria monocytogenes infection in mice. Data in brief, 7:995–998. (Co-1st author) (Non-SCI).
  8. Kuo, T.F., Chen, T.Y., Jiang, S.T., Chen, K.W., Chiang, Y.M., Hsu, Y.J., Liu, Y.J., Chen, H.M., Yokoyama, K.K., Tsai, K.C., Yeh, H.H., Chen, Y.R., Yang W.C.*. (2017) Protein disulfide isomerase a4 as a novel therapeutic target of cancer, Oncogene, 36: 5484–5496 (R/C= 26/244；IF=7.971)
  9. Bartolome, A.P., Villaseñor, I.M., Lin, Y.L., M. Libardo, D.J., Angeles-Boza, A.M., Yang, W.C. (2017) Cytotoxic property of Streptocaulon baumii extracts and their isolated compounds against different human cancer cell lines. Philippine Science Letters, 10(2) 89-97 (Non-SCI)
  10. van der Touw, W, Kang, K., Luan, Y., Ma, G., Mai, S., Qin, L., Bian, G., Mungamuri, S. K., Zhang, R., Hu, H.M., Zhang, C.C., Aaronson, S.A., Feldmann, M., Yang, W.C., Chen, S.H.*, and Pan, P.Y.* (2018) Glatiramer acetate enhances myeloid-derived suppressor cell function via recognition of paired Ig-like receptor B, 201(6):1727-1734 (Cover page) (R/C= 44/154；IF=4.886)
  11. Kuo, L.C., Song,Y.Q., Yao,C.A., Cheng, I.H., Chien,C.T., Lee,G.C., Yang, W.C.,  and Lin*, Y.S. (2019) Ginkgolide A Prevents the Amyloid-β-Induced Depolarization of Cortical Neurons, J. Agric. Food Chem., 67 (1) :  81–89 (R/C= 6/52；IF=4.192)
  12. Yang, W.C., Yang, C.Y., Liang, Y.C., Li, W.Q., Chung, C.Y., Yang, M.T., Kuo, T.F., Lin, C.F., Liang, C.L., Chang, C.L.T.(2019). Anti-coccidial properties and mechanisms of an edible herb, Bidens pilosa, and its active compounds for coccidiosis, Scientific Reports. 9:2896 (R/C=17/71;IF=3.998)
  13. Liang, Y.C., Lin, C.J., Chou, F.S., Yang, M.T., Yang, W.C.* and Chang, C.L.T.* (2020) Toxicity study of Bidens pilosa in animals, eJTCM, 10(2): 150-157 (Non-SCI)
  14. Apaya, M.K.#, Kuo, T.F.#,  Yang, M.T.#, Yang, G., Hsiao, C.L., Chang, S.B., Lin, Y. and Yang W.C.*. (2020) Phytochemicals as modulators of β-cells and immunity for the therapy of type 1 diabetes: Recent discoveries in pharmacological mechanisms and clinical potential, Pharmacological Research.  156 : 104754 (R/C= 19/270； IF=5.893)
  15. Yang, M.T., Kuo, T.F., Chung, K.F., Liang, Y.C., Yang, C.W., Lin, C.Y., Feng, C.S, Cheng,C.W., Lee, T.H., Hsiao, C.L.* and Yang W.C.*. (2020) Authentication, compound characterization and anti-bacterial activity of two common Artemisia species in Taiwan. Food Chemistry 333: 127458 (R/C= 6/139；IF=6.306)
  16. Kuo, T.F.#, Yang, G.#, Chen, T.Y.#, Wu,Y.C., Minh, H.T.N., Chen, L.S., Chen, W.C., Huang, M.K., Liang, Y.C., and Yang W.C.*. (2021) Bidens pilosa: Nutritional Value and Benefits for Metabolic Syndrome. Food Frontier 2(1): 32-45 (Non-SCI)
  17. Yang, M.T., Chang, W.H., Kuo, T.F., Shen, M.Y., Yang, C.W., Tien, Y.J., Lai, B.Y., Chang, Y.C, Chen, Y.R., and Yang W.C.*. (2021) Identification of novel biomarkers for pre-diabetic diagnosis using a combinational approach. Frontier in Endocrinology. 12:64133 (R/C= 32/145 ;IF= 5.555)
  18. Kuo, T.F., Chang, C.L.T., Hsu, S.W., Huang, S.H., Chang, C.L.T, Feng, C.S., Huang, M.G., Chen, T.Y., Yang, M.T., Jiang, S.T., Wen, T.Y., Yang, C.Y., Hung, Y.J., Kao, S.H., Tsai, K.C., Yang, G., Yang W.C.*. (2021) Pdia4 regulates β-cell pathogenesis in diabetes: molecular mechanism and targeted therapy. EMBO Molecular Medicine, e11668 (R/C=5/188; IF= 12.137)
  19. Chuang, J.H., Yang, W.C., Lin, Y* (2021) Glutamatergic Neurons Differentiated from Embryonic Stem Cells: An Investigation of Differentiation and Associated Diseases International Journal of Molecular Sciences 22(9):4592 (R/C=67/297 ; IF= 5.923)
  20. Wang, J.S., Tsai, P.H., Tseng, K.F., Chen, F.Y., Yang, W.C., Shen, M.Y.* (2021) Sesamol Ameliorates Renal Injury-Mediated Atherosclerosis Via Inhibition of Oxidative Stress/IKKα/p53. Antioxidants 10 (10): 1519 (R/C=6/63 ; IF= 6.312)
  21. C.S., Pan, B.Y., Tsai, P.H., Chen, T.M, Chen, F.Y., Yang, W.C. and Shen, M.Y. (2021) Kansuinine A Ameliorates Atherosclerosis and Human Aortic Endothelial Cell Apoptosis by Inhibiting Reactive Oxygen Species Production and Suppressing IKKβ/IκBα/NF-κB Signaling 22 :10309 (R/C=67/297 ; IF= 5.923)
  22. Yang, M.T., Lin, Y.X., Yang, G., Kuo, T.F.,Liang, Y.C., Lee, T.H., Chang, C.L.T* and Yang, W.C.* (2021) Functional and Mechanistic Studies of Two Anti-coccidial Herbs, Bidens pilosa and Artemisia indica. Planta Medica. doi: 10.1055/a-1527-9715 (R/C= 23/70 ; IF= 3.352)
  23. Chen, T.Y. Yang, C.Y., Yang, M.T., Kuo, T.F., Chang, C.L.T., Chen, C.L., Chiu, C.F., Yu, Y.H., Yang, G., Lee, T.H., Yang, W.C.* (2021) Protein disulfide isomerase a4 promotes lung cancer development via the Stat3 pathway in stromal cells. Clinical and Translational Medicine. Accepted (R/C=10/140 ; IF= 11.492)